Oral Surgery & Extractions
MRONJ (medication & jaw healing)
How certain bone medications affect dental surgery, and how we reduce the risk.
Concern
Affected jaw healing
Medicines
Bisphosphonates, denosumab
Risk
Low overall
Key step
Tell us your full history
Overview
Some medications that strengthen bone or treat certain cancers — including bisphosphonates and denosumab — can rarely affect how the jaw heals after dental surgery, a condition called medication-related osteonecrosis of the jaw (MRONJ). The overall risk is low, but telling us you take these medicines lets us plan carefully and keep it that way.
Common questions
Which medications matter?
Mainly antiresorptive and antiangiogenic medicines (for example bisphosphonates, denosumab and some cancer therapies), whether tablets or injections. Always tell us your full medical and medication history.
Does this mean I can't have a tooth out?
Not usually. It means we assess your individual risk, plan the gentlest approach, and may take extra steps. For most people, needed treatment still goes ahead.
How is the risk reduced?
Ideally a dental check-up before starting these medicines, keeping your mouth healthy, minimising surgery where possible, and careful aftercare and review.
Dr Rick Iskandar · Reviewed June 2026